|
Institutional Holders
|
|
|
Total Number of Holders
|
125
|
|
% of Shares Outstanding
|
81.57%
|
|
Total Shares Held
|
42,294,321
|
|
Total Value of Holdings
|
$1,771,709,106.69
|
|
Net Activity
|
8,738,118
|
|
|
|
Top 5 Holders
|
Shares Held
|
Shares Changed
|
|
RA CAPITAL MANAGEMENT, L.P.
|
9,165,652
|
0
|
|
FMR LLC
|
7,749,009
|
3,077,796
|
|
ORBIMED ADVISORS LLC
|
4,275,553
|
957,626
|
|
BVF INC/IL
|
2,919,818
|
(1,660,000)
|
|
ADAGE CAPITAL PARTNERS GP, L.L.C.
|
2,775,672
|
1,420,197
|
See All Results
|
|
|
|
Insider Trades
|
|
| | Last 3 mos. | Last 12 mos. | | Number of Insider Trades | 4 | 8 | | Number of Buys | 0 | 4 | | Number of Sells | 4 | 4 | | Net Activity |
(3,822,721)
|
(778,151)
|
|
|
|
|
|
|
5% Ownership (SC 13D & SC 13G Filings)
|
|
|