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SPYRE THERAPEUTICS, INC. (SYRE) Ownership Summary
Institutional Holders
Total Number of Holders 130
% of Shares Outstanding 98.94%
Total Shares Held 50,381,119
Total Value of Holdings $1,459,037,206.24
Net Activity 18,023,245
 
Top 5 Holders Shares Held Shares Changed
FMR LLC 7,507,983 924,228
FAIRMOUNT FUNDS MANAGEMENT LLC 4,018,101 3,639,680
RTW INVESTMENTS, LP 3,258,360 1,025,600
PERCEPTIVE ADVISORS LLC 3,031,018 474,339
VR ADVISER, LLC 2,685,448 513,666

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Insider Trades
 Last 3 mos.Last 12 mos.
Number of Insider Trades13
Number of Buys01
Number of Sells12
Net Activity (18,531) (2,641,935)
 
Top 5 TradesShares Traded Date
BURROWS SCOTT L18,5319/3/2024
TURTLE CAMERON4002/15/2024
BURROWS SCOTT L134,95312/22/2023
TURTLE CAMERON723,44011/24/2023

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5% Ownership (SC 13D & SC 13G Filings)
View Form   Filer  Received  Period 
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View Filing in HTMLView Filing in RTFView Filing in PDFView Filing in Original Format  SC 13G/A   FMR LLC  06/10/24   File this document to a folder.
View Filing in HTMLView Filing in RTFView Filing in PDFView Filing in ExcelView Filing in Original Format  SC 13D/A   FAIRMOUNT FUNDS MANAGEMENT LLC  04/25/24   File this document to a folder.
View Filing in HTMLView Filing in RTFView Filing in PDFView Filing in ExcelView Filing in Original Format  SC 13G/A   AVORO CAPITAL ADVISORS LLC  04/23/24   File this document to a folder.
View Filing in HTMLView Filing in RTFView Filing in PDFView Filing in Original Format  SC 13G/A   FMR LLC  03/11/24   File this document to a folder.
View Filing in HTMLView Filing in RTFView Filing in PDFView Filing in ExcelView Filing in Original Format  SC 13G/A   VENROCK HEALTHCARE CAPITAL PARTNERS III, L.P.  02/14/24   File this document to a folder.