|
Institutional Holders
|
|
|
Total Number of Holders
|
127
|
|
% of Shares Outstanding
|
61.81%
|
|
Total Shares Held
|
59,890,827
|
|
Total Value of Holdings
|
$522,846,919.71
|
|
Net Activity
|
(5,687,254)
|
|
|
|
Top 5 Holders
|
Shares Held
|
Shares Changed
|
|
DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C)
|
11,077,927
|
0
|
|
RA CAPITAL MANAGEMENT, L.P.
|
10,860,977
|
1,401,299
|
|
ORBIMED ADVISORS LLC
|
9,240,887
|
0
|
|
SR ONE CAPITAL MANAGEMENT, LP
|
4,012,903
|
0
|
|
FRANKLIN RESOURCES INC
|
2,950,963
|
(1,147,534)
|
See All Results
|
|
|
|
Insider Trades
|
|
| | Last 3 mos. | Last 12 mos. | | Number of Insider Trades | 16 | 54 | | Number of Buys | 0 | 9 | | Number of Sells | 16 | 45 | | Net Activity |
(1,000,000)
| 7,031,037 |
|
|
|
|
|
|
5% Ownership (SC 13D & SC 13G Filings)
|
|
|